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ARTICLE |

THREE CASES OF ACUTE ENCEPHALITIS TREATED WITH SPECIFIC SERUM

HENRY F. HELMHOLZ, M.D.; EDWARD C. ROSENOW, M.D.
JAMA. 1922;79(25):2068-2071. doi:10.1001/jama.1922.02640250022009.
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ABSTRACT

Ever since the pandemic of influenza, an unusually large series of cases of encephalitis has been observed. With each succeeding year the number of cases has gradually decreased; but if our experience is any criterion, there is still an excess of encephalitis over and above that previous to the pandemic.

Our clinical material during the past year has consisted in large measure of the sequels and chronic residues of encephalitis, but we have also observed a number of acute cases, in three of which we used lumbar drainage and the usual symptomatic treatment, with a specific serum recently prepared by one of us (E. C. R.). This serum was obtained from a horse repeatedly injected with a streptococcus isolated from a patient suffering from typical encephalitis.

REPORT OF CASES 

Case 1.  —B., a girl, aged 5 years, became ill, Dec. 15, 1921. She weighed at birth 7% pounds (3.5 kg.);

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