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JAMA. 1922;79(11):867-870. doi:10.1001/jama.1922.02640110007003.
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The conditions diagnosed in a study of 485 cases showing lesions of the genitalia clinically suspicious of venereal disease are presented in Table 1.

This series constitutes all the material of this type seen in the skin and syphilis clinic of the outpatient department of Lakeside Hospital and in private practice by me and my associate, Dr. Harold N. Cole, from Aug. 1, 1920, to Feb. 1, 1922, a period of eighteen months. The methods employed in coming to a final diagnosis will be briefly outlined.

HISTORY  The history of the case is often helpful, if accurate data can be obtained. In chancroid, the incubation period is short, as a rule less than ten days; while in syphilis the incubation period is usually from ten days to six weeks. We have found the history to be the least reliable of all clinical aids, and it should not be the sole


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