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S. H. Geist, M.D.
JAMA. 1920;74(11):752-753. doi:10.1001/jama.1920.02620110042021.
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To the Editor:  —In a paper published in the American Journal of Obstetrics and Diseases of Women and Children (March, 1914) it was pointed out that the occurrence of sarcomas or of sarcomatous change in uterine fibromyomas was relatively frequent.A careful study of 250 cases was made at that time, and twelve sarcomas were found that had been removed by operation. In only two instances was the diagnosis made, and then only at the time of operation. It was shown that symptomatically these malignant cases as a rule offered no distinctive diagnostic criteria, and for that reason it was difficult to differentiate clinically the malignant from the nonmalignant cases. In other words, it was practically impossible to say definitely that a case supposedly a fibromyoma and therefore amenable to roentgen-ray therapy was not really harboring a malignant tumor. Two of the patients after operation developed extensive recurrences and died;


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