Miles F. Porter, M.D.
JAMA. 1920;74(7):479. doi:10.1001/jama.1920.02620070047029.
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To the Editor:  —In your editorial, January 13, page 329, occurs the question: "May premature delivery be associated with the milder grades of hyperthyroidism?" I believe that it is pretty generally conceded by students of the subject that hyperthyroidism produces premature delivery. I myself have observed a number of cases that seem to substantiate this opinion. The report of one of these cases I am quite sure was published, but I cannot just now cite the reference. It was a case of premature delivery from separation of the placenta, which separation, I concluded after careful survey of the case, was caused by a hyperactive thyroid. Crotti, in his book on "Thyroid and Thymus," page 368, speaking of exophthalmic goiter in pregnancy, says: "It predisposes the patient to uterine hemorrhages and may result in the death of the fetus."


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