JAMA. 1919;73(25):1868-1871. doi:10.1001/jama.1919.02610510006004.
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Much of the mystery and confusion that surrounds the subject of mixed tumors of the testis has been cleared up in recent years by the work of Schlagenhaufer and Pick abroad, and of Ewing in this country. These men have shown that practically all of the so-called mixed tumors of the testis are teratomas having tissues composed of the three primary germinal layers, the ectoderm being represented by cysts lined with flat epithelium, the entoderm by cysts lined with columnar or ciliated epithelium, and the mesoderm by connective tissue, cartilage, bone, and muscle. These primary tissues may form organs and blood vessels in a more or less orderly imitation of a fetus. Very often one type of tissue grows more rapidly than the others, and overshadows or even suppresses them, so that the presence of only one tissue is not absolute proof against its teratomatous origin. Should the tumor undergo


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