In reports of the pandemic of influenza and its complications, reference has been made to toxemia and to the symptoms of shock and meningitis. Thus, Keeton and Cushman1 mention the delirium observed early as well as late in the disease, and liken the shock to that following operations. They noted the engorged conjunctival blood vessels, so constantly seen in the acute exanthems, in a number of the patients suffering from influenza and pointed out the difficulty not infrequently encountered in differentiating influenza from meningitis.
Evidence of this systemic infection is also present in statements regarding toxemia and delirium in the reports made by Friedlander and his co-workers,2 and by Synnott and Clark.3 Strouse and Bloch4 mention one case, in the 500 studied clinically by them, at first suggestive of meningitis but with the spinal fluid unchanged except for increased tension. Nervous manifestations were observed in the