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June 14, 1919, Vol 72, No. 24 >
ARTICLE | June 14, 1919

GLYCURESIS VERSUS GLYCOSURIA

JAMA. 1919;72(24):1772. doi:10.1001/jama.1919.02610240060013.
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Not long ago we commented on the suggestion of S. R. Benedict1 that progress in the study of carbohydrate metabolism would be more rapid if the term "glycosuria" were abolished. According to his contention, some sugar elimination, however small, takes place continuously through the kidneys. This contention has been advanced by others to explain the finding of reducing substances in the urine of presumably healthy persons. Since glycosuria implies a sudden point at which sugar appears in the urine, a term is needed to express the constant presence of sugar in normal urine and an excess of sugar elimination above normal limits. Benedict accordingly coined the expression "glycuresis" to signify the increased absolute elimination of sugar per hour as compared with the control period. The experimental data indicated that food ingestion is the controlling factor in physiologic sugar elimination.

These interesting conclusions were not entirely convincing owing to the

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