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June 14, 1919, Vol 72, No. 24 >
ARTICLE | June 14, 1919

MITOCHONDRIA

JAMA. 1919;72(24):1770-1771. doi:10.1001/jama.1919.02610240058011.
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Microscopic anatomy, which is still diligently inquiring into the nature of cell structure, has recently shifted its interest in no small measure from the nucleus to the cytoplasm. As a result, a definite type of cytoplasmic granules now known as mitochondria, a term first introduced by Benda in 1899, has become recognized and has been extensively studied. E. V. Cowdry1 has recently summarized our present knowledge concerning these bodies. They have a variety of shapes: sometimes they are filamentous or rodlike, and again pear-shaped or granular. While their size varies greatly in different cells and even in a single cell, it seems to be the rule that the cells of certain tissues in different animals have similar mitochondria. Cowdry believes that here is shown a correlation of cellular function and morphology.

The fundamental importance of mitochondria is evidenced by their wide distribution. They have been demonstrated in plants, from

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