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June 7, 1919, Vol 72, No. 23 >
ARTICLE | June 7, 1919

OXIDATION IN THE BODY

JAMA. 1919;72(23):1679-1680. doi:10.1001/jama.1919.02610230033012.
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The answer to the question as to how the all important oxidations in the body are brought about is almost as obscure today as it was a hundred years ago when this mode of energy transformation in the animal organism was first being discussed. Not long ago, in touching on this perplexing subject, reference was made to the view, recently championed by several physiologists, that an enzyme (catalase) having the property of liberating oxygen from peroxids is principally responsible for oxidation in the body.1 The justification for this contention has been derived essentially from comparisons of the catalase content of the blood in conditions differing essentially in the extent of the oxidative changes that may be assumed to be associated with them. For example, food and exercise promote oxidative metabolism in the organism; the catalase content of the blood was reported to be correspondingly augmented. The association of cause

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