The tissue changes resulting from injection of tuberculin in or near tuberculous foci have been most remarkable in some instances.
White and Marcy1 report good results from such treatment of a tuberculous tongue; Patterson2 gives his final results in eye conditions treated similarly, and Pottenger3 remarks on the good results obtained in laryngeal cases treated by tuberculin locally.
The following case is of interest and study of similar cases may help us to get a better understanding of immunity in tuberculosis:
S. A., showing a moderately advanced case running normal temperature and pulse, complained of irritation in the throat. Examination of the larynx revealed a localized area of inflammation on the upper right of the epiglottis posteriorly. This was treated with different local applications, but regardless of treatment the area extended and ulceration with slight edema resulted. Amputation was considered, but it was thought best first to