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COMPARATIVE PROGNOSIS OF TUBERCULOUS LESIONS OF RIGHT AND LEFT LUNG:  REPORT OF FIVE HUNDRED CASES

LOUIS MARK, M.D.
JAMA. 1919;72(19):1348-1351. doi:10.1001/jama.1919.02610190010004.
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During the routine reexamination of patients in the women's service at the Ohio State Sanatorium, it had been my observation that cases with the greater amount of active involvement in the left lung made progress slower toward quiescence than cases in which the right lung was more involved. A few years ago, while doing a large number of necropsies on tuberculous subjects, I repeatedly noticed that in the majority of cases of bilateral tuberculosis the right lung showed considerable involvement at the apex, with a marked tendency toward fibrosis; whereas the left lung was usually heavily infiltrated from the apex to the base, with a thickening of the pleura and very firm pleural adhesions but with very little fibrosis of the lung. From this I judged that the initial lesion had been in the right lung, but that the left lung showed the greater amount of active involvement.

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