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March 22, 1919, Vol 72, No. 12 >
ARTICLE | March 22, 1919

THE SYNTHETIC POWERS OF THE MAMMARY GLAND

JAMA. 1919;72(12):864. doi:10.1001/jama.1919.02610120026014.
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The mammary gland has long been believed to be the seat of important synthetic activities. The casein, the sugar and to a lesser degree some of the fats of milk are different from any protein, carbohydrate or fat found elsewhere in the body. They have a specific character long recognized. What are the limits of the synthetic power of cells which can produce such distinct and specialized products? Can it produce them entirely de novo as the growing plant builds the most complex organic derivatives from very simple compounds, or is the synthetic capacity of the gland limited to a less profound sort of rearrangement of preformed fragments? It is well known in the case of the nutrition of growth that certain amino-acids are indispensable for the synthesis of tissue proteins. The capacity of the body to produce glycocoll seems to be almost unlimited. But without tryptophan or lysin new

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AAM 2010;304:1493-1495.
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BMJ 2010;341:c5893-c1494.
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