This is not a textbook of physiology as usually understood, but a thorough review of those parts of physiology and biochemistry that bear most directly on general clinical medicine, with particular reference to the needs of the advanced students and of physicians. An enumeration of the different parts will give an idea of the scope of the book: the physicochemical basis of physiologic processes, the circulating fluids, circulation of the blood, respiration, digestion, excretion of urine, metabolism, endocrine organs or ductless glands, and the central nervous system. The first part discusses in lucid fashion the great physical and physicochemical principles of physiology; the exposition here given of osmosis, the laws of solution, gas laws, ionization, hydrogen-ion concentration, regulation of neutrality, and acidosis, colloids and ferments should prove of great interest and help to physicians and students in their efforts to advance their real understanding of disease. By far the larger