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February 15, 1919, Vol 72, No. 7 >
ARTICLE | February 15, 1919

CALCIUM AND INFANTILE TETANY

JAMA. 1919;72(7):496-497. doi:10.1001/jama.1919.02610070034019.
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As The Journal recently pointed out,1 Noël Paton and his collaborators of Glasgow University have come to the conclusion that the tetany of animals deprived of their parathyroid glands and the idiopathic tetany of man are identical as regards their characters and metabolism. The implication is that an error in the chemical exchanges of the organism results in an intoxication by guanidin derivatives, a disturbance in parathyroid function being assumed to underlie the abnormal conditions. So far, however, as infantile tetany is concerned, Howland and Marriott2 of the Department of Pediatrics at the Johns Hopkins University insist that enough studies have been made to show that parathyroid lesions in infancy are the exception and not the rule. Furthermore, they maintain that parathyroid lesions as severe as have been found after tetany may occur in patients who, during life, have shown absolutely no evidences of this symptom.

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