Frequent desire to urinate, slight or severe pain with or without straining when urinating, sometimes made worse by emptying the bladder and generally associated with persistent discomfort in the bladder, sufficient frequently to interfere with sleep, are the symptoms of the still other symptom that is here meant by the term "irritable bladder." The cases are generally of long standing and come with a history of prolonged and various treatment, including kidney remedies, washings of the bladder, correction of the uterus, operations on the perineum or rectum or both, and, finally if not all the time, opiates, sometimes resulting in drug habituation. As a rule these patients have lost flesh and have become highly nervous, which results in their frequent classification as "hysterics." They are as a rule sore trials to their medical attendants, the last of whom in desperation has sought relief at the hands of a consultant.
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