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January 18, 1919, Vol 72, No. 3 >

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ARTICLE | January 18, 1919

EDEMA OF THE BRAIN IN THE INFECTIOUS DISEASES

C. T. SHARPE, M.D.
JAMA. 1919;72(3):159-162. doi:10.1001/jama.1919.02610030005002.
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ABSTRACT

Little is to be found in the literature relative to edema of the brain in the infectious diseases as a clinical entity, and much less, therefore, if anything, as to edema as a clinical type of an infectious disease. We are all familiar with the occurrence of meningismus in acute diseases, and during the febrile stage are not surprised to have some evidence of it; but how many of us are prepared to take the position that edema does, in some cases, develop to such an extent that it masks the ordinary clinical picture of the disease and may occasion doubt as to the diagnosis?

Edema of the brain may and does appear at different periods in the course of the infectious diseases. When it occurs early it may hide the true nature of the illness and it has been noticed on several occasions that with the predominance of this

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