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Chester B. Moore, B.S., M.D.
JAMA. 1918;71(25):2056-2057. doi:10.1001/jama.1918.26020510002009b.
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A not uncommon pelvic focus for the lodgment of the gonococcus is the gland of Skene. In this minute epithelial pocket such an infection may persist indefinitely in spite of local applications. Even if the ducts are exposed and medicinal injections directed into them with a hypodermic needle, the infection may continue without interruption. Often it is possible to express a few or several drops of pus week after week, and month after month, along with such oft-repeated treatment. Furthermore, this minute gland may remain in a chronic state of suppuration without a local symptom, the focus of infection being discovered only in the course of a general pelvic examination. Unless one makes an attempt to express the contents of these ducts, this focus may be entirely overlooked. In this type of gonorrheal infection of Skene's gland nothing less than the complete destruction of the gland will terminate the disease


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