0
ARTICLE |

A FURTHER CONSIDERATION OF COMPLEMENT FIXATION IN TUBERCULOSIS

V. H. MOON, M.Sc., M.D.
JAMA. 1918;71(14):1127-1133. doi:10.1001/jama.1918.02600400027009.
Text Size: A A A
Published online

The demonstration of antibodies in the circulating blood by complement fixation was first accomplished by Bordet and Gengou1 and its application was made to tuberculosis by them several years before Wassermann and Bruck successfully applied the test in syphilis. If medical men should desire a less cumbersome term than the complement fixation test for tuberculosis it seems they could not do better than to term it simply "the Bordet test." The term has the advantage of brevity. It is historically accurate, and would fittingly perpetuate the name of the distinguished French investigator who first demonstrated the part played by complement in immune reactions—a discovery by which his German contemporaries were not slow to profit.

Wassermann and Bruck2 made experiments with complement fixation in tuberculosis before they developed the test for syphilis, and subsequently Citron3 made similar experiments. In these earlier tests, Koch's "old tuberculin" was used as

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();