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AGGLUTININ RESPONSE AFTER ARMY TRIPLE TYPHOID VACCINATION

ERIC A. FENNEL, M.D.
JAMA. 1918;70(25):1915-1919. doi:10.1001/jama.1918.26010250001006.
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ABSTRACT

The efficiency of typhoid vaccination in the United States Army, as developed by Colonel Russell, is now a matter of history. That typhoid inoculation results in the production of an effective immunity over a considerable period of time has long since been proved, both experimentally and clinically. On the one hand, agglutinin and bactericidal experiments, and on the other, the vital statistics of the Army since the typhoid inoculation became an order, are quite conclusive.

The history of paratyphoid and the mixed inoculations is now being made. There is little reason to doubt that they will be as successful as the typhoid inoculations. To determine to what extent specific agglutinins for the three types of organisms used by the Army were produced by the men inoculated, at the suggestion of Lieutenant-Colonel Whitmore, the series of cases here summarized were studied. The series included men who had had no typhoid or

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