Study concept and design: Durante, Costante, Nicolucci, Filetti.
Acquisition, analysis, or interpretation of data: Durante, Costante, Lucisano, Bruno, Meringolo, Paciaroni, Puxeddu, Torlontano, Tumino, Attard, Lamartina, Filetti.
Drafting of the manuscript: Durante, Nicolucci, Filetti.
Critical revision of the manuscript for important intellectual content: All the authors.
Statistical analysis: Lucisano, Nicolucci.
Obtained funding: Filetti.
Administrative, technical, or material support: Lucisano, Paciaroni, Puxeddu, Lamartina.
Study supervision: Durante, Costante, Bruno, Meringolo, Torlontano, Tumino, Attard, Nicolucci.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: The study was funded by research grants from the Umberto Di Mario Foundation, Banca d’Italia, and the Italian Thyroid Cancer Observatory (ITCO) Foundation.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; in the preparation, review, or approval of the manuscript; or in the decision to submit the manuscript for publication.
Additional Contributions: The authors thank David Cooper, MD, Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, for invaluable comments and suggestions, and to Marian Everett Kent, BSN (Rome, Italy), for medical editing services. No compensation for the contribution was received by Dr Cooper. Ms Kent’s contribution was funded by research grants from the Umberto Di Mario Foundation. We also thank all the medical doctors, residents, students, and nurses who participated in this study for their important contributions.