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ARTICLE |

A CASE OF TUMOR OF THE HYPOPHYSIS

CHARLES HARRISON FRAZIER, M.D.; JAMES HENDRIE LLOYD, M.D.
JAMA. 1913;61(18):1626-1627. doi:10.1001/jama.1913.04350190044014.
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ABSTRACT

MEDICAL NOTES BY DR. LLOYD  The following case occurred recently in my wards at the Philadelphia General Hospital. As a hypophyseal case it is noteworthy for two things, namely, the presence of marked pressure or "neighborhood" symptoms, and the absence of a distinct cachexia either of acromegaly or of the dystrophia adiposogenitalis. The patient was neither infantile nor acromegalic; he was not overgrown or undergrown; he was neither too fat nor too lean; neither too large nor too small; his sexual organs were normally developed and he did not have a "hypotrichosis" either of his face or of his pubes; he had no craving for sweets, nor had he any diabetes or polyuria, and his temperature range was normal. What he did have was rapid onset of blindness with headache and vomiting, and he presented, under the Roentgen ray, the evidence of a pituitary tumor. In addition to headache he had

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