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JAMA. 1913;61(13_part_1):1042-1043. doi:10.1001/jama.1913.04350130036012.
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From the paper of L. Casamajor1 I learn that in the mines and factories of America cases of manganese toxicosis occur not infrequently; cases such as have been described, first, in 1823, by Couper; in 1901 by myself2 and Embden and then by Friedel. That induces me to communicate briefly to my American colleagues my clinical observations in connection with that interesting and well-known morbid state.

I think that the nervous affections among workmen in factories who are occupied with the production of potassium permanganate and among workmen in mills who are working in an atmosphere full of dust of manganates and in workmen in manganese mills, are produced through the inspiration of dust containing manganates.

I reach that conclusion from the circumstance that in the factory from which I gathered my observations, after the spread of dust had been prevented, the workmen were thenceforth free from such affections. The


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