JAMA. 1913;60(22):1682-1690. doi:10.1001/jama.1913.04340220006003.
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It is now almost two years since the first, attempt to utilize the following views was made by James J. Hogan, who relieved a case of acute nephritis with anuria by injecting an alkaline hypertonic sodium chlorid solution. Since that time the simple principles of treatment proposed have been tried on many private and hospital patients, SO that it has been possible to arrive at some conclusions regarding their actual value. I wish to discuss this question briefly in the following pages. At the same time, in order to satisfy a number of medical men, I desire to outline in greater detail the method of treatment which will in my judgment insure the best results.

For a detailed statement of my colloid-chemical views on the nature and cause of nephritis I must refer the reader to previous discussions.1 They may be briefly expressed as follows:


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