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Herman C. Little, M.D.
JAMA. 1913;60(12):899. doi:10.1001/jama.1913.04340120025014.
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History.  —Patient, aged 24, monk, entered the Yale Mission Hospital, Changsha, China, Oct. 23, 1912, with tumor of the left side of the face and neck of ten years' duration. It began as a small nodule just below the angle of the left lower jaw and increased gradually to the size shown in Figures 1 and 2. Until three months ago the skin of the tumor remained intact, and except for a hypersensitiveness of the skin and tension due to the weight of the growth, there was very little pain. Three months ago the skin broke in two places shown in Figure 2, and since then has broken in several other smaller places.

Examination.  —A large, nodular tumor, so heavy that it caused the patient considerable inconvenience, limited all movements of the head and neck, and had to be carried in his arms when he walked and held in his


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