JAMA. 1913;60(11):822-824. doi:10.1001/jama.1913.04340110028010.
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The following case of leukemia presented several features of unusual clinical and pathologic interest. Like many cases of leukemia, its type was very irregular and in the absence of any definite knowledge of the etiology of this disease, its classification, if any be attempted, provides a wide field for discussion.

History  —The patient was a well-developed, robust man, aged 23, a hotel waiter, who had come under observation for the early secondary stage of syphilis eighteen months before his death. The inguinal nodes at this time were slightly swollen, but the spleen and liver were not apparently enlarged. The urine showed no special change. His blood was not examined at this time. He had suffered from gonorrhea five months previous to his coming to the hospital, but denied any other illness before this. There was no history of any previous enlargement of the lymph-nodes. He had originally come from Greece


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