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THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1913;60(3):206-210. doi:10.1001/jama.1913.04340030036018.
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TUMORS OF THE UROGENITAL TRACT IN ANILINDYE WORKERS  In 1895 Rehn described three tumors of the urinary bladder in fuchsin workers, and after a critical study of his cases concluded that the liberation of such products as toluidin, nitrobenzene and anilin, when crude fuchsin is heated, in all probability was an important factor in the causation of the tumors. Since 1895, forty-one cases of tumors of the urogenital system in anilin-dye workers have been reported. Leuenberger1 in a recent article on this subject reports eighteen additional cases. On reviewing the death statistics of the city of Basel for the period 1901-1910, Leuenberger finds that deaths due to tumors of the urinary passages were thirty-three times more numerous in anilin-dye workers than in workmen of other classes. Statistics of the Basel University clinic indicate that over 50 per cent. of all cases of tumors of the urinary bladder in patients

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