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THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1910;55(25):2158-2161. doi:10.1001/jama.1910.04330250054017.
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RECENT STUDIES ON TYPHUS FEVER  It will be recalled that Nicolle of Tunis, in Africa, recently succeeded in transmitting typhus fever to the macacus monkey, and that Anderson and Goldberger, working independently with the disease as it is found in Mexico City, were able to infect monkeys with blood taken from typhus patients. These results were further confirmed by the investigations of Ricketts and Wilder. Recently Gaviño and Girard1 report the transmission of typhus to monkeys of an inferior species, namely, the Ateles vellerosus, indigenous to Mexico, by subcutaneous injections of blood from typhus patients. The animals, after an incubation period of eleven to fourteen days, succumb to prostration and a high fever. An exanthematic eruption, such as occurs almost constantly in man, is absent, but the thermal elevation and other symptoms are regarded as sufficiently characteristic to permit the diagnosis of typhus. Immunity is conferred by a single

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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