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VARIOUS FORMS OF EXPERIMENTAL DIABETES AND THEIR SIGNIFICANCE FOR DIABETES MELLITUS

J. J. R. MACLEOD, M.B., Ch.B., D.P.H.
JAMA. 1910;55(25):2133-2139. doi:10.1001/jama.1910.04330250029008.
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In the short time allotted in this symposium to the study of experimental diabetes or glycosuria, I shall not of course attempt to give any general review of all the experimental conditions which may cause reducing substances to appear in the urine. It will be more profitable to devote the greater part of my time to a study of the simplest and best-known form of experimental glycosuria, namely, to that which results from stimulation of certain portions of the nervous system.

I shall, then, briefly consider the relationship to this comparatively simple form of glycosuria of some of the other experimental forms, such as those produced by asphyxia and by the influence of certain ductless glands. Its relationship to clinical diabetes I shall, however, omit, for the reason that there is very little definite information on which to base conclusions.

Before going farther, it may be well to call attention

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