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METABOLISM IN DIABETES

GRAHAM LUSK
JAMA. 1910;55(25):2105-2107. doi:10.1001/jama.1910.04330250001001.
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"When Bernard had completed his lectures in the winter term of 1854-55, few questions in physiology were apparently more completely settled than that of the glycogenic function of the liver. The consequences of this doctrine were of the utmost importance, for, once settled that sugar is the product of animal as well as vegetable organisms and that an organ can be found which is singly concerned in its production, we would have at once in the exaggerated performance of a normal function, the proximate cause of diabetes. There had been from the first no lack of opposition to Bernard's views, but so skilfully had he defended his position that, at the time of which we make mention the very objections of his critics had only served to increase, in the eyes of the candid, the magnitude of his triumph."

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