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E. P. LYON, Ph.D.; GUY L. QUALLS, B.S., M.D.
JAMA. 1910;55(6):455-459. doi:10.1001/jama.1910.04330060007002.
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The continued use by some physicians of the preparations of Cactus grandiflorus is perhaps sufficient justification for the publication of another investigation into their pharmacologic properties.

PART I.—EXPERIMENTS WITH CACTINA (SULTAN DRUG CO.)  The experiments to be described were begun at the request of Mr. F. Sultan, of St. Louis, Mo., who furnished the Cactina and also the Erlanger sphygmomanometer employed in part of the work. The investigation of Cactina was undertaken with the understanding that Mr. Sultan should furnish any apparatus needed, but that no compensation was to be made for the work, and that the results should be published after a report had been made to Mr. Sultan. Such a report was sent to him on July 4, 1908. Since that date some further experiments with Cactina and all those with Cactin (Abbott Alkaloidal Co.) have been performed.

EXPERIMENTS ON ANIMALS  It has been claimed that the effects


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