Author Contributions: Dr Pavkov had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Pavkov, Bennett, Knowler, Nelson.
Acquisition of data: Pavkov, Knowler, Krakoff, Sievers, Nelson.
Analysis and interpretation of data: Pavkov, Knowler, Krakoff, Sievers, Nelson.
Drafting of the manuscript: Pavkov.
Critical revision of the manuscript for important intellectual content: Bennett, Knowler, Sievers, Nelson.
Statistical analysis: Pavkov, Knowler, Nelson.
Obtained funding: Knowler.
Administrative, technical, or material support: Knowler, Krakoff, Sievers, Nelson.
Study supervision: Bennett, Knowler, Nelson.
Financial Disclosures: None reported.
Funding/Support: This research was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases. Dr Pavkov is supported by a mentor-based fellowship award from the American Diabetes Association.
Role of the Sponsor: The sponsor of this study had no role in any aspect of the study design; in the collection, analysis, and interpretation of data; or in the development of the manuscript. The manuscript was submitted to the National Institute of Diabetes and Digestive and Kidney Diseases before submission.
Acknowledgment: We thank the members of the Gila River Indian Community for participating in this investigation.