Author Contributions: Dr Breteler had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Bos, Witteman,
Hofman, Koudstaal, Breteler
Acquisition of data: Bos, van Rijn,
Analysis and interpretation of data:
Bos, Koudstaal, Breteler
Drafting of the manuscript: Bos, Koudstaal,
Critical revision of the manuscript for important intellectual content: Bos, van Rijn, Witteman, Hofman, Koudstaal,
Statistical analysis: Bos
Obtained funding: Hofman, Koudstaal,
Study supervision: Koudstaal, Breteler
Financial Disclosures: None reported.
Funding/Support: The Rotterdam Study is supported by Erasmus Medical Center Rotterdam, the Erasmus University Rotterdam, the Netherlands Organization for Scientific Research, the Netherlands Organization for Health Research and Development, the Research Institute for Diseases in the Elderly, the Ministry of Education,
Culture and Science, and the Ministry of Health, Welfare, and Sports.
This study was supported by the Netherlands Organization for Scientific Research grants 904-61-093 and 918-46-615.
Role of the Sponsors: The sponsors had no role in the design and conduct of the study, in the collection,
management, analysis, and interpretation of the data, or in the preparation,
review, or approval of the manuscript.
Additional Contributions: We thank the general practitioners and pharmacists of the Ommoord district to the Rotterdam Study for their participation.