Author Contributions: Ms Lui had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Cauley, Hochberg,
Acquisition of data: Cauley, Hochberg,
Ensrud, Hillier, Nevitt, Cummings.
Analysis and interpretation of data:
Cauley, Hochberg, Lui, Palermo, Ensrud, Hillier, Nevitt.
Drafting of the manuscript: Cauley.
Critical revision of the manuscript for important intellectual content: Hochberg, Lui, Palermo, Ensrud, Hillier,
Statistical analysis: Lui, Palermo.
Obtained funding: Cauley, Ensrud, Nevitt,
Administrative, technical, or material support:
Financial Disclosures: Dr Cauley reported receiving research support from Merck & Company, Eli Lilly &
Company, Pfizer Pharmaceuticals, and Novartis Pharmaceuticals; receiving consulting fees from Eli Lilly & Company and Novartis Pharmaceuticals;
and serving on the speaker's bureau for Merck & Co Inc. Dr Hochberg reported receiving research support from the National Institutes of Health and serving as a consultant for the following companies that have products related to osteoporosis and/or vertebral fractures:
Amgen, GlaxoSmithKline, Merck & Co Inc, Novartis Pharma AG, Proctor & Gamble Pharmaceutical Co, Roche Laboratories, and Wyeth Pharmaceuticals.
Dr Cummings reported receiving research support from Amgen, Pfizer,
Novartis, Eli Lilly and Co and consulting fees or honoraria from Eli Lilly and Co, Zelos, Merck and Co, Novartis, GlaxoSmithKline, Procter & Gamble, and Aventis. No other authors reported financial disclosures.
Funding/Support: The Study of Osteoporotic Fractures is supported by funding from the National Institutes of Health. The National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Institute on Aging provided support under grants AG05407, AR35582, AG05394, AR35584, AR35583, R01 AG005407,
R01 AG027576-22, 2 R01 AG005394-22A1, and 2 R01 AG027574-22A1.
Role of the Sponsor: The National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Institute on Aging did not participate in the design and conduct of the study, in the collection, analysis, and interpretation of the data, or in the preparation, review, or approval of the manuscript.