Cardiovascular epidemiology has a rich, collaborative, and productive history. Beginning in 1948, the Framingham Heart Study was instrumental in identifying, for instance, high blood pressure and dyslipidemia as major risk factors for coronary heart disease and stroke.1 Subsequent clinical trials identified safe and effective treatments for these conditions. In the last several decades, the widespread use of medications for hypertension and dyslipidemia have prevented or delayed the onset of cardiovascular disease for millions of US residents. At the 60th anniversary of the Framingham study, a new approach to cardiovascular disease epidemiology is about to be tested.
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