Study concept and design: Burt, Futterer, Oliveira.
Acquisition, analysis, or interpretation of data: Burt, Balabanov, Han, Sharrack, Morgan, Quigley, Yaung, Helenowski, Jovanovic, Spahovic, Arnautovic, Lee, Benefield, Futterer, Burman.
Drafting of the manuscript: Burt, Han, Quigley, Jovanovic, Arnautovic.
Critical revision of the manuscript for important intellectual content: Burt, Balabanov, Han, Sharrack, Morgan, Yaung, Helenowski, Spahovic, Lee, Benefield, Futterer, Oliveira, Burman.
Statistical analysis: Burt, Han, Sharrack, Quigley, Helenowski, Jovanovic, Spahovic, Arnautovic.
Administrative, technical, or material support: Burt, Han, Quigley, Yaung, Spahovic, Lee, Benefield.
Study supervision: Burt, Quigley, Spahovic.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Balabanov reported serving as a consultant to and serving on speakers bureaus for Teva Pharmaceuticals and Biogen Idec. Dr Burman reported serving as a consultant to Biogen Idec, Hospira, Merck Serono, and Genzyme. No other disclosures were reported.
Funding/Support: This study was made possible by financial support from the Danhakl family, the Cumming Foundation, the Zakat Foundation, the McNamara Purcell Foundation, and Morgan Stanley and Company.
Role of the Funder/Sponsor: The funders/sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.