Study concept and design: Livingstone, Levin, Joss, Leese, Pearson, Petrie, Colhoun.
Acquisition, analysis, or interpretation of data: Livingstone, Levin, Looker, Lindsay, Wild, Joss, Leese, Leslie, McCrimmon, Metcalfe, McKnight, Morris, Pearson, Philip, Sattar, Traynor, Colhoun.
Drafting of the manuscript: Livingstone, Levin, Leese, Leslie, Metcalfe, Colhoun.
Critical revision of the manuscript for important intellectual content: Livingstone, Looker, Lindsay, Wild, Joss, Leese, McCrimmon, Metcalfe, McKnight, Morris, Pearson, Petrie, Philip, Sattar, Traynor, Colhoun.
Statistical analysis: Livingstone, Levin, Metcalfe.
Obtained funding: Lindsay, Wild, Leese, Petrie, Colhoun.
Administrative, technical, or material support: Lindsay, Wild, Leese, Metcalfe, McKnight, Petrie, Philip, Traynor.
Study supervision: Leese, Morris, Colhoun.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Petrie reported receiving personal fees from Novo Nordisk; grants, personal fees, and nonfinancial support from sanofi-aventis; grants and nonfinancial support from Merck Serono; grants and personal fees from AstraZeneca; personal fees from Alere; personal fees from Lilly; nonfinancial support from Itamar Medical; grants from Juvenile Diabetes Research Foundation; and grants and personal fees from Quintiles. Dr Lindsay reported receiving personal fees from Eli Lilly Limited and personal fees from Novo Nordisk Limited. Dr Colhoun reported receiving grants, personal fees, and costs for advisory panel participation from Pfizer Inc; costs for advisory panel and contribution to sponsored clinical trial from sanofi-aventis and Novartis Pharmaceuticals; costs for advisory panel, and contribution to sponsored clinical trial and research support from Eli Lilly & Co; grants and research support from and shareholder with Roche Pharmaceuticals; grants from Boehringer Ingelheim; grants from AstraZeneca LP. No other disclosures were reported.
Funding/Support: This study was supported by grant WT086113 from the Wellcome Trust SHIP Grant and from the Chief Scientist Office of the Scottish Government.
Role of the Funder/Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank the members of the Scottish Diabetes Research Network, the Scottish Renal Registry, and the SCI-DC team.