Individuals with homocystinuria, a rare genetic disorder associated with markedly elevated plasma homocysteine levels (ie, 100-300 μmol/L [to convert to mg/dL, divide by 7.397]—at least 10 times higher than the general population), experience rapidly progressive atherosclerosis and associated thromboembolic events in early adulthood. This observation prompted the “homocysteine hypothesis” that moderately elevated homocysteine levels might be of causal relevance to cardiovascular disease in the general population.1
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 7
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Users' Guides to the Medical Literature
Interpreting Apparently "Positive" Trials
All results at
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.