Malaria remains a leading cause of morbidity and mortality globally. An estimated 3 billion individuals live in areas of risk and the disease causes more than 1 million deaths annually.1 Even in the United States, where endemic malaria has been eradicated for decades, an average of 1200 cases are reported annually.2 The articles in this issue of JAMA on malaria address a number of important issues, including the financial and logistic challenges of implementing new technologies for disease prevention and diagnosis; improvement in understanding risk factors and disease severity, particularly in children; and treatment and surveillance approaches in the face of evolving drug resistance.
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