Author Contributions: Ms Bulkow had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Singleton, Hennessy, Hammitt, Hurlburt, Butler, Rudolph.
Acquisition of data: Singleton, Hennessy, Bulkow, Zulz, Hurlburt, Rudolph, Parkinson.
Analysis and interpretation of data: Singleton, Hennessy, Bulkow, Hammitt, Zulz, Butler, Rudolph.
Drafting of the manuscript: Singleton, Hennessy, Bulkow, Hammitt, Zulz, Hurlburt, Butler, Rudolph, Parkinson.
Critical revision of the manuscript for important intellectual content: Singleton, Hennessy, Bulkow, Hammitt, Zulz, Butler, Rudolph.
Statistical analysis: Singleton, Hennessy, Bulkow, Zulz, Rudolph.
Obtained funding: Hennessy, Parkinson.
Administrative, technical, or material support: Singleton, Hennessy, Zulz, Hurlburt, Butler, Rudolph, Parkinson.
Study supervision: Singleton, Hennessy, Parkinson.
Financial Disclosures: None reported. All authors are US federal government employees.
Funding/Support: Funding was provided by the CDC as part of the authors' normal work duties. Dr Singleton presented pneumococcal disease data at a Wyeth Pharmaceuticals' advisory board meeting. Wyeth Vaccines has agreed to fund a pneumococcal colonization study to be conducted by Arctic Investigations Program, CDC.
Role of Sponsors: The CDC participated in the design and collection of the study data; collection, management, analysis, and interpretation of the data; and preparation, review or approval of the manuscript.
Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the CDC. Mention of a product under development does not constitute endorsement of that product.
Acknowledgment: We thank the CDC’s Arctic Investigations Program staff members for their contribution to this study: Helen Peters, RN, Alisa Reasonover, BS, Catherine Dentinger, RN, MPH, Ken Petersen, MD, Michael Bruce, MD, Kip Baggett, MD, Lyn Zanis, BS, Karen Miernyk, BS, Carolynn Debyle, BS, Cindy Hamlin, RN, Jim Gove, RN, Marcella Harker-Jones, BS, and Debra Parks, BS. No specific compensation was received for their work on this study. We also thank Bernard Beall, PhD, of the CDC for providing multilocus sequence typing results.