In 1997, a total of 2,639 households were screened, and 2,300 persons agreed to participate (response rate: 84.4% in Raleigh, 88.9% in Greensboro). Of the 2,300 participants, 617 had diabetes, and 407 agreed to participate in an examination. In the follow-up survey, 3,540 households were screened, and 3,083 persons agreed to participate (response rate: 78.9% in Raleigh, 83.5% in Greensboro). Of the 3,083 participants, 729 had diabetes, and 435 agreed to participate in an examination. A trained phlebotomist conducted the health examinations, which included measurements of height and weight to determine body mass index (BMI), defined as weight (kg) divided by height (m2), and fasting blood draws. Blood samples were transported to a central laboratory to assess HbA1c and lipid levels (HDL, LDL, total cholesterol, and triglycerides). The following criteria were used to classify persons as having glycemic, lipid, and BMI measures outside the ranges recommended by the American Diabetes Association: HbA1c >7%, HDL cholesterol <40 mg/dL, LDL cholesterol ≥130 mg/dL, total cholesterol ≥200 mg/dL, triglycerides ≥200 mg/dL, and BMI ≥30.10 Smoking and insulin use were also assessed.