We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
From the Archives Journals |

Genes Involved in the Pathogenesis of Primary Open-Angle Glaucoma

Louis R. Pasquale, MD
JAMA. 2007;297(3):306-307. doi:10.1001/jama.297.3.306.
Text Size: A A A
Published online


Quigley HA, Broman AT.The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90:262-267
PubMed   |  Link to Article[[XSLOpenURL/10.1136/bjo.2005.081224]]
Hewitt AW, Craig JE, Mackey DA.Complex genetics of complex traits: the case of primary open-angle glaucoma. Clin Exper Ophthalmol. 2006;34:472-484
PubMed   |  Link to Article[[XSLOpenURL/10.1111/ceo.2006.34.issue-5]]
Pederson JE, Gaasterland DE.Laser-induced primate glaucoma, I: progression of cupping. Arch Ophthalmol. 1984;102:1689-1692
PubMed   |  Link to Article[[XSLOpenURL/10.1001/archopht.1984.01040031373030]]
Sommer A, Tielsch JM, Katz J.  et al. Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans: the Baltimore Eye Survey. Arch Ophthalmol. 1991;109:1090-1095
PubMed   |  Link to Article[[XSLOpenURL/10.1001/archopht.1991.01080080050026]]
Duggal P, Klein AP, Lee KE, Klein R, Klein BE, Bailey-Wilson JE.Identification of novel genetic loci for intraocular pressure: a genomewide scan of the Beaver Dam Eye Study. Arch Ophthalmol. 2007;125:74-79
Link to Article[[XSLOpenURL/10.1001/archopht.125.1.74]]
Kalenak JW, Paydar F.Correlation of intraocular pressures in pairs of monozygotic and dizygotic twins. Ophthalmology. 1995;102:1559-1564
Allayee H, de Bruin TW, Michelle Dominguez K.  et al. Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p. Hypertension. 2001;38:773-778
PubMed   |  Link to Article[[XSLOpenURL/10.1161/hy1001.092617]]
Rice T, Rankinen T, Province MA.  et al. Genome-wide linkage analysis of systolic and diastolic blood pressure: the Quebec Family Study. Circulation. 2000;102:1956-1963
PubMed   |  Link to Article[[XSLOpenURL/10.1161/01.CIR.102.16.1956]]
Lin DY.Evaluating statistical significance in two-stage genomewide association studies. Am J Hum Genet. 2006;78:505-509
PubMed   |  Link to Article[[XSLOpenURL/10.1086/500812]]
Kass MA, Heuer DK, Higginbotham EJ.  et al. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120:701-713, 829-830
PubMed   |  Link to Article[[XSLOpenURL/10.1001/archopht.120.6.701]]


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.