Author Contributions: Drs Bibbins-Domingo and Whooley had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Bibbins-Domingo, Whooley.
Acquisition of data: Bibbins-Domingo, Whooley.
Analysis and interpretation of data: Bibbins-Domingo, Gupta, Na, Wu, Schiller, Whooley.
Drafting of the manuscript: Bibbins-Domingo, Gupta, Na, Schiller, Whooley.
Critical revision of the manuscript for important intellectual content: Bibbins-Domingo, Wu, Schiller, Whooley.
Statistical analysis: Bibbins-Domingo, Gupta, Na, Whooley.
Obtained funding: Bibbins-Domingo, Whooley.
Administrative, technical, or material support: Bibbins-Domingo, Wu, Whooley.
Study supervision: Bibbins-Domingo, Whooley.
Financial Disclosures: None reported.
Funding/Support: This study was supported by grants to Dr Bibbins-Domingo from the Robert Wood Johnson Foundation (Amos Medical Faculty Development award), the National Heart, Lung, and Blood Institute (contract N01-HC-95095), and the University of California, San Francisco, Research Evaluation and Allocation Committee. The Heart and Soul Study was funded by the Department of Veterans Affairs (Washington, DC), the National Heart, Lung, and Blood Institute (grant R01 HL079235), the American Federation for Aging Research (Paul Beeson Scholars Program), the Robert Wood Johnson Foundation (Faculty Scholars Program), the Nancy Kirwan Heart Research Fund, San Francisco, Calif, and the Ischemia Research and Education Foundation. The NT-proBNP assays were funded by Roche Diagnostics Corporation, Indianapolis, Ind.
Role of the Sponsor: Neither the funding organizations nor Roche Diagnostics had any role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation or approval of the manuscript.