Author Contributions: Drs Wolf and Miller had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Wolf, Miller, Taub, Morris, Light, Nichols-Larsen.
Acquisition of data: Wolf, Winstein, Taub, Uswatte, Morris, Giuliani, Light, Nichols-Larsen.
Analysis and interpretation of data: Wolf, Winstein, Miller, Taub, Uswatte, Nichols-Larsen.
Drafting of the manuscript: Wolf, Winstein, Miller, Uswatte.
Critical revision of the manuscript for important intellectual content: Wolf, Winstein, Miller, Taub, Uswatte, Morris, Giuliani, Light, Nichols-Larsen.
Statistical analysis: Wolf, Miller.
Obtained funding: Wolf, Miller, Taub, Nichols-Larsen.
Administrative, technical, or material support: Wolf, Winstein, Miller, Taub, Uswatte, Morris, Light, Nichols-Larsen.
Study supervision: Wolf, Winstein, Taub, Uswatte, Morris, Light, Nichols-Larsen.
Financial Disclosures: None reported.
EXCITE Investigators:Executive committee: Steven L. Wolf, PhD, PT, principal investigator, Emory University School of Medicine, Atlanta, Ga; Carolee Winstein, PhD, PT, co–principal investigator, University of Southern California, Los Angeles; J. Phillip Miller, AB, director, EXCITE data management center, Washington University, St Louis, Mo. Steering committee and training center: Edward Taub, PhD, Gitendra Uswatte, PhD, and David Morris, PhD, PT, University of Alabama at Birmingham; Carol Giuliani, PhD, PT, University of North Carolina, Chapel Hill; David Good, MD, Wake Forest University, Winston-Salem, NC; Kathye Light, PhD, PT, University of Florida, Gainesville; Deborah Nichols-Larsen, PhD, PT, Ohio State University, Columbus. Data safety and monitoring board: Bruce Dobkin, MD, chair, University of California at Los Angeles; Rebecca Craik, PhD, PT, Arcadia University, Glenside, Pa; Terrance Therneau, PhD, Mayo Clinic, Rochester, Minn.
Funding/Support: This research was supported by National Institutes of Health grant HD 37606 from the National Center for Medical Rehabilitation Research (National Institute of Child Health and Human Development) and the National Institute of Neurological Diseases and Stroke.
Role of the Sponsors: The funders did not participate in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript. All data acquisition was inspected and reviewed annually by the designated data safety and monitoring board. The National Center for Medical Rehabilitation Research, National Institute for Child Health and Human Development oversaw the formulation and activities of the data safety and monitoring board.
Acknowledgment: We thank our site coordinators, evaluators, and trainers, members of the data management center, and members of the administrative and training cores at Emory University and the University of Alabama at Birmingham, respectively, without whose tireless and diligent efforts this study could not have been initiated or completed. Special thanks to Sarah Blanton, DPT, NCS, Department of Rehabilitation Medicine, Emory University School of Medicine, EXCITE project coordinator, for diligent follow-up on serious adverse events data to confirm their accuracy.