Author Contributions: Dr Press had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Petersen, Hadley, Kinney, Miesfeldt, Lu, Lynch, Burke, Press.
Acquisition of data: Lindor, Petersen, Hadley, Kinney, Miesfeldt, Lu.
Analysis and interpretation of data: Lindor, Petersen, Kinney, Lu.
Drafting of the manuscript: Lindor, Petersen, Hadley, Kinney, Miesfeldt, Lu.
Critical revision of the manuscript for important intellectual content: Lindor, Petersen, Hadley, Miesfeldt, Lu, Lynch, Burke, Press.
Statistical analysis: Miesfeldt.
Obtained funding: Press.
Administrative, technical, or material support: Petersen, Hadley, Kinney, Miesfeldt, Lu, Press.
Study supervision: Lindor, Hadley, Lynch, Press.
Financial Disclosures: None reported.
Funding/Support: The work for this article was supported by grant 3R01HG001885-03S2 from the National Institutes of Health. This article represents the cumulative work of the Cancer Genetics Studies Consortium, a set of 15 projects funded by the National Human Genome Institute, the National Cancer Institute, the National Institute of Mental Health, and the National Institute of Nursing Research. Dr Press was supported by a grant from the National Human Genome Research Institute's Ethical, Legal, and Social Implications Program. Mr Hadley was supported by the Intramural Research Program of the National Human Genome Research Institute, National Institutes of Health.
Role of the Sponsor: The funding sponsor had no role in the design and conduct of the analysis and interpretation contained in this clinical review, which is the independent work of the authors.
Acknowledgment: Elizabeth Thomson, PhD, of the National Human Genome Research Institute's Ethical, Legal and Social Implications program, contributed to each stage of the development of the Cancer Genetics Studies Consortium. Dr Thomson was not compensated for this work.