Author Contributions: Dr Millikan had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Carey, Perou, Moorman, Millikan.
Acquisition of data: Livasy, Dressler, Conway, Edmiston, Deming, Geradts, Cheang, Nielsen, Moorman, Millikan.
Analysis and interpretation of data: Carey, Perou, Livasy, Dressler, Cowan, Conway, Karaca, Troester, Tse, Deming, Cheang, Nielsen, Earp, Millikan.
Drafting of the manuscript: Carey, Perou, Tse, Nielsen, Millikan.
Critical revision of the manuscript for important intellectual content: Carey, Perou, Livasy, Dressler, Cowan, Conway, Karaca, Troester, Edmiston, Deming, Geradts, Cheang, Nielsen, Moorman, Earp, Millikan.
Statistical analysis: Tse, Deming, Cheang, Millikan.
Obtained funding: Perou, Dressler, Conway, Earp, Millikan.
Administrative, technical, or material support: Carey, Livasy, Dressler, Cowan, Conway, Karaca, Troester, Edmiston, Nielsen, Moorman, Millikan.
Study supervision: Carey, Perou, Dressler, Conway, Edmiston, Nielsen, Millikan.
Financial Disclosures: None reported.
Funding/Support: This work was supported by an award to the University of North Carolina for a Breast Cancer Specialized Program of Research Excellence (SPORE) from the National Cancer Institute (NIH/NCI P50-CA58223), a grant from the General Clinical Research Centers Program of the Division of Research Resources/National Institutes of Health (M01RR00046 awarded to Dr Carey), and by the NCI (RO1-CA-101227-01 awarded to Dr Perou).
Role of the Sponsor: All study funding was from public grants for scientific research. The funding organizations had no role in the design and conduct of the study; the collection, analysis, and interpretation of the data; or the preparation, review, or approval of the manuscript.
Previous Presentation: This work was presented in part at the 40th Annual Meeting of the American Society of Clinical Oncology; New Orleans, La; June 2004.
Acknowledgment: For their critical review, we thank Barbara Rimer, PhD, School of Public Health; and Paul Godley, MD, PhD, and Matthew G. Ewend, MD, School of Medicine, University of North Carolina. They were not compensated for their time.