Author Contributions: Dr Peterson had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Peterson, Lytle, Pollack, Newby, Gibler, Ohman.
Acquisition of data: Peterson, Pollack, Harrington, Ohman.
Analysis and interpretation of data: Peterson, Roe, Mulgund, DeLong, Brindis, Smith, Pollack, Newby, Harrington.
Drafting of the manuscript: Peterson, DeLong, Lytle.
Critical revision of the manuscript for important intellectual content: Peterson, Roe, Mulgund, DeLong, Lytle, Brindis, Smith, Pollack, Newby, Harrington, Gibler, Ohman.
Statistical analysis: Peterson, Mulgund, DeLong.
Obtained funding: Peterson, Roe, Harrington, Gibler, Ohman.
Administrative, technical, or material support: Peterson, Roe, Harrington, Ohman.
Study supervision: Peterson, Roe, Ohman.
Financial Disclosures: Drs Peterson, Roe, Brindis, Smith, Pollack, Newby, Harrington, Gibler, and Ohman have reported receiving research support from Schering-Plough Corp, Bristol-Myers Squibb/Sanofi-Aventis Pharmaceuticals Partnership, and Millennium Pharmaceuticals. No other authors reported financial disclosures.
Funding/Support: This study was supported by CRUSADE, a National Quality Improvement Initiative of the Duke Clinical Research Institute, which was funded by the Schering-Plough Corporation. Bristol-Myers Squibb/Sanofi-Aventis Pharmaceuticals Partnership and Millennium Pharmaceuticals provided additional funding support. Dr Peterson is also the recipient of grant R01 AG025312-01A1 from the National Institute on Aging.
Role of the Sponsors: Although none of the sponsors were directly involved in design and conduct of the study, in the collection, management, analysis, and interpretation of the data, or in the preparation of the manuscript, the sponsors all reviewed the submitted manuscript.