Meningitis can lead to permanent neurological damage or death. In adults and older children, it presents with fever, a stiff neck, fatigue, and headache. In infants, these signs may be absent, and the infant may only display fussiness, lethargy, and inability to feed. Individuals with pneumonia usually have shortness of breath, high fever, a cough, fatigue, and chest pains. Meningitis and sepsis are the most life-threatening pneumococcal diseases. Individuals with meningitis or sepsis must receive rapid diagnosis and treatment to prevent severe multiple organ failure and death.