Author Contributions: Dr Poehling had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Poehling, Griffin, Whitney, Reingold, Farley, Schaffner.
Acquisition of data: Poehling, Griffin, Craig, Whitney, Lexau, Thomas, Harrison, Hadler, Farley, Anderson, Schaffner.
Analysis and interpretation of data: Poehling, Talbot, Griffin, Whitney, Zell, Reingold, Schaffner.
Drafting of the manuscript: Poehling, Talbot, Reingold, Schaffner.
Critical revision of the manuscript for important intellectual content: Talbot, Griffin, Craig, Whitney, Zell, Lexau, Thomas, Harrison, Reingold, Hadler, Farley, Anderson.
Statistical analysis: Poehling, Zell.
Obtained funding: Whitney, Reingold, Farley, Schaffner.
Administrative, technical, or material support: Griffin, Craig, Whitney, Thomas, Reingold, Farley, Anderson, Schaffner.
Study supervision: Talbot, Griffin, Reingold, Schaffner.
Financial Disclosures: Ms Zell reports that she owns stock in Merck and Pfizer. No other authors reported financial disclosures.
Funding/Support: This work was supported in part by Centers for Disease Control and Prevention (CDC) Emerging Infections grant U50/CCU416123 (data collection and management) and by Association of Teachers of Preventive Medicine/CDC Cooperative Agreement TS-0825 (travel support to obtain data). Dr Poehling received support from the Robert Wood Johnson Generalist Physician Faculty Scholars Program.
Role of the Sponsor: Data analysis and interpretation and the preparation of the manuscript were performed independently of the funding organizations.
Acknowledgment: We thank all members of the Active Bacterial Core surveillance network and the CDC Emerging Infections Program, especially Tamar Pilishvili, MPH, Carolyn Wright, BS, and Angela Roberson, MStat, for data assistance; Richard Facklam, PhD, CDC Emerging Infections Program, for serotype determination; the Minnesota Department of Health Public Health Laboratory for serotype determination and antibiotic susceptibility testing; Jim Jorgensen, PhD, University of Texas Health Sciences Center, San Antonio, for antibiotic susceptibility testing; Peter Herzfeld, MS, New York State Department of Health, Bureau of Vital Statistics, for the 2003 vital statistics from New York; Robin McClenton, for obtaining vital statistics data, Ed Mitchel, MS, for data assistance, and Shannon Dyer, BA, for secretarial assistance at Vanderbilt University School of Medicine; and Kathryn M. Edwards, MD, for critically reviewing the manuscript.