Dyspepsia, also called indigestion, is a problem that most adults experience at least once in their lifetime. Upper abdominal discomfort, nausea, vomiting, and belching are all symptoms of dyspepsia. Indigestion is often related to consumption of too much food, especially heavy or greasy foods, eating late at night, smoking, alcohol consumption, or life stress. For some individuals, dyspepsia occurs regularly and becomes a health and quality-of-life issue. The April 5, 2006, issue of JAMA includes an article about dyspepsia.