Author Contributions: Dr Whang had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Whang, Manson, Hu, Albert.
Acquisition of data: Manson, Rexrode, Willett, Stampfer, Albert.
Analysis and interpretation of data: Whang, Manson, Hu, Chae, Rexrode, Stampfer, Albert.
Drafting of the manuscript: Whang, Albert.
Critical revision of the manuscript for important intellectual content: Manson, Hu, Chae, Rexrode, Willett, Stampfer, Albert.
Statistical analysis: Whang, Hu, Chae, Rexrode, Willett, Albert.
Obtained funding: Manson, Rexrode, Willett, Albert.
Administrative, technical, or material support: Manson, Rexrode, Willett, Stampfer.
Study supervision: Albert.
Financial Disclosures: None reported.
Funding/Support: This work was supported by grants CA-87969, HL-34594, and HL-03783 from the National Institutes of Health.
Role of the Sponsor: The funding sources for this study played no role in the design or conduct of the study; collection, management, analysis, or interpretation of the data; or in the preparation, review, or approval of the manuscript prior to publication.
Previous Presentation: An abstract based on this manuscript was presented orally at a meeting of the Heart Rhythm Society from May 4-7, 2005, in New Orleans, La.
Acknowledgment: We are indebted to the participants in the Nurses' Health Study for their outstanding commitment and cooperation.